Description
| Product Name: | FOXL1 Transcription Factor Activity Assay |
| Product Code: | TFAB00111 |
| Target: | FOXL1 |
| Synonyms: | Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC-7 |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie FOXL1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | FOXL1: Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 16q24 Cellular Component: nucleus Molecular Function:DNA binding; sequence-specific DNA binding; DNA bending activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; organ morphogenesis; heart development; proteoglycan biosynthetic process; multicellular organismal development; regulation of Wnt receptor signaling pathway; visceral mesoderm-endoderm interaction involved in midgut development |
| NCBI Summary: | This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q12952 |
| NCBI GenInfo Identifier: | 13638268 |
| NCBI Gene ID: | 2300 |
| NCBI Accession: | Q12952.2 |
| UniProt Secondary Accession: | Q12952,Q17RR1, Q9H242, |
| UniProt Related Accession: | Q12952 |
| Molecular Weight: | 345 |
| NCBI Full Name: | Forkhead box protein L1 |
| NCBI Synonym Full Names: | forkhead box L1 |
| NCBI Official Symbol: | FOXL1 |
| NCBI Official Synonym Symbols: | FKH6; FKHL11; FREAC7 |
| NCBI Protein Information: | forkhead box protein L1; forkhead-like 11; forkhead-related protein FKHL11; forkhead-related transcription factor 7 |
| UniProt Protein Name: | Forkhead box protein L1 |
| UniProt Synonym Protein Names: | Forkhead-related protein FKHL11; Forkhead-related transcription factor 7; FREAC-7 |
| Protein Family: | Forkhead box protein |
| UniProt Gene Name: | FOXL1 |
| UniProt Entry Name: | FOXL1_HUMAN |