Name: FOXL1 Antibody (PACO17899)
SKU: PACO17899
Availability: OutOfStock

Antibody Name:	FOXL1 Antibody (PACO17899)
Antibody SKU:	PACO17899
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:1000-1:5000, WB:1:500-1:2000
Species Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide of human FOXL1

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T cells, mouse intestinum tenue tissue, Primary antibody: PACO17899(FOXL1 Antibody) at dilution 1/850, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds.

Background:

This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors.

Synonyms:

forkhead box L1

UniProt Protein Function:	FOXL1: Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors.
UniProt Protein Details:	Protein type:DNA-binding Chromosomal Location of Human Ortholog: 16q24 Cellular Component: nucleus Molecular Function:DNA binding; sequence-specific DNA binding; DNA bending activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; organ morphogenesis; heart development; proteoglycan biosynthetic process; multicellular organismal development; regulation of Wnt receptor signaling pathway; visceral mesoderm-endoderm interaction involved in midgut development
NCBI Summary:	This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]
UniProt Code:	Q12952
NCBI GenInfo Identifier:	13638268
NCBI Gene ID:	2300
NCBI Accession:	Q12952.2
UniProt Secondary Accession:	Q12952,Q17RR1, Q9H242,
UniProt Related Accession:	Q12952
Molecular Weight:	345
NCBI Full Name:	Forkhead box protein L1
NCBI Synonym Full Names:	forkhead box L1
NCBI Official Symbol:	FOXL1
NCBI Official Synonym Symbols:	FKH6; FKHL11; FREAC7
NCBI Protein Information:	forkhead box protein L1; forkhead-like 11; forkhead-related protein FKHL11; forkhead-related transcription factor 7
UniProt Protein Name:	Forkhead box protein L1
UniProt Synonym Protein Names:	Forkhead-related protein FKHL11; Forkhead-related transcription factor 7; FREAC-7
Protein Family:	Forkhead box protein
UniProt Gene Name:	FOXL1
UniProt Entry Name:	FOXL1_HUMAN

Antibodies	ELISA Kits
Anti-FOXL1 Antibody (CAB2931)	FOXL1 Transcription Factor Activity Assay
FOXL1 Antibody (PACO00819)	FOXL1 Colorimetric Cell-Based ELISA

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)