Description
Antibody Name: | FOXL1 Antibody |
Antibody SKU: | PACO00819 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Monkey |
Immunogen: | synthesized peptide derived from the Internal region of human FoxL1. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | FOXL1; FKHL11; FREAC7; Forkhead box protein L1; Forkhead-related protein FKHL11; Forkhead-related transcription factor 7; FREAC-7 |
UniProt Protein Function: | FOXL1: Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 16q24 Cellular Component: nucleus Molecular Function:DNA binding; sequence-specific DNA binding; DNA bending activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; organ morphogenesis; heart development; proteoglycan biosynthetic process; multicellular organismal development; regulation of Wnt receptor signaling pathway; visceral mesoderm-endoderm interaction involved in midgut development |
NCBI Summary: | This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012] |
UniProt Code: | Q12952 |
NCBI GenInfo Identifier: | 13638268 |
NCBI Gene ID: | 2300 |
NCBI Accession: | Q12952.2 |
UniProt Secondary Accession: | Q12952,Q17RR1, Q9H242, |
UniProt Related Accession: | Q12952 |
Molecular Weight: | 345 |
NCBI Full Name: | Forkhead box protein L1 |
NCBI Synonym Full Names: | forkhead box L1 |
NCBI Official Symbol: | FOXL1 |
NCBI Official Synonym Symbols: | FKH6; FKHL11; FREAC7 |
NCBI Protein Information: | forkhead box protein L1; forkhead-like 11; forkhead-related protein FKHL11; forkhead-related transcription factor 7 |
UniProt Protein Name: | Forkhead box protein L1 |
UniProt Synonym Protein Names: | Forkhead-related protein FKHL11; Forkhead-related transcription factor 7; FREAC-7 |
Protein Family: | Forkhead box protein |
UniProt Gene Name: | FOXL1 |
UniProt Entry Name: | FOXL1_HUMAN |