FOXB2 Antibody (PACO17881)
- SKU:
- PACO17881
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FOXB2 Antibody (PACO17881) |
| Antibody SKU: | PACO17881 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human FOXB2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO17881(FOXB2 Antibody) at dilution 1/5, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO17881(FOXB2 Antibody) at dilution 1/5, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic development. The defining feature of FOX proteins is the forkhead box, a sequence of 80 to 100 amino acid, forming a motif that binds to DNA. This forkhead motif is also known as the winged helix due to the butterfly-like appearance of the loops in the protein structure of the domain. Forkhead genes are a subgroup of the helix-turn-helix class of proteins. The FOXF2 gene encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta. |
| Synonyms: | Forkhead box B2 |
| UniProt Protein Function: | FOXB2: Transcription factor (Probable). |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 9q21.2 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding |
| UniProt Code: | Q5VYV0 |
| NCBI GenInfo Identifier: | 74747718 |
| NCBI Gene ID: | 442425 |
| NCBI Accession: | Q5VYV0.1 |
| UniProt Related Accession: | Q5VYV0 |
| Molecular Weight: | 45,581 Da |
| NCBI Full Name: | Forkhead box protein B2 |
| NCBI Synonym Full Names: | forkhead box B2 |
| NCBI Official Symbol: | FOXB2 |
| NCBI Official Synonym Symbols: | bA159H20.4 |
| NCBI Protein Information: | forkhead box protein B2 |
| UniProt Protein Name: | Forkhead box protein B2 |
| Protein Family: | Forkhead box protein |
| UniProt Gene Name: | FOXB2 |
| UniProt Entry Name: | FOXB2_HUMAN |
| Antibodies | ELISA Kits |
| FOXB2 Antibody (PACO00817) | FOXB2 Transcription Factor Activity Assay |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
