Fos B Monoclonal Antibody
- SKU:
- CAB24339
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | Fos B Monoclonal Antibody |
| Product Code: | CAB24339 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61057 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa treated by TPA |
| Cellular Location: | Nucleus |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Fos B(NP_006723.2). |
| Sequence: | MFQAF PGDYD SGSRC SSSPS AESQY LSSVD SFGSP PTAAA SQECA GLGEM PGSFV PTVTA ITTSQ DLQWL VQPTL ISSMA QSQGQ PLASQ PPVVD PYDMP |
| Synonyms: | AP-1, G0S3, GOS3, GOSB |
| Calculated MW: | 36kDa |
| Observed MW: | 38kDa/48kDa |
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