Formyl-Histone H2B-K108 Monoclonal Antibody

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SKU:
CAB0032
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC

Description

Product Name:Formyl-Histone H2B-K108 Monoclonal Antibody
Product Code:CAB0032
Reactivity:Human, Mouse, Rat, Other (Wide Range)
Applications:Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC2492
Reactivity:Human, Mouse, Rat, Other (Wide Range)
Tested Applications:IHC-P, ELISA
Key Applications:Immunohistochemistry
Recommended Dilution:IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Human liver, Mouse lung, Rat brain
Cellular Location:Chromosome, Nucleus

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.

Immunogen:A synthesized peptide derived from human Histone H2B (formyl K108).
Sequence:Email for sequence
Synonyms:H2B, H2BE, H2BQ, GL105, H2B.1, H2BFQ, H2BGL105, H2B-GL105, HIST2H2BE
Calculated MW:14kDa
Observed MW:15kDa
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