Description
Product Name: | Formyl-HIST1H2BC (K108) Antibody |
Product Code: | PACO65129 |
Size: | 50µL |
Target Names: | HIST1H2BC |
Species Reactivity: | Human |
Host Species: | Rabbit |
Antigen Species: | Human |
Tested Applications: | ELISA, ICC; Recommended dilution: ICC:1:10-1:100 |
Isotype: | IgG |
Clone ID: | N/A |
Conjugate: | Non-conjugated |
Clonality: | Polyclonal |
Antigen: | Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (104-115aa) |
Form: | Liquid |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Aliases: | Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK |
Uniprot ID: | P62807 |
Background: | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Research Area: | Epigenetics and Nuclear Signaling |