FMN2 Antibody (PACO19672)
- SKU:
- PACO19672
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FMN2 Antibody (PACO19672) |
| Antibody SKU: | PACO19672 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human FMN2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19672(FMN2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19672(FMN2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity. |
| Synonyms: | formin 2 |
| UniProt Protein Function: | FMN2: Belongs to the formin homology family. Cappuccino subfamilyProtein type: Nucleolus; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 1q43Cellular Component: endoplasmic reticulum membrane; cytoplasmic vesicle membrane; microvillus; perinuclear region of cytoplasm; plasma membrane; nucleolus; spindle; cell cortex; cytosol; actin cytoskeletonMolecular Function: actin bindingBiological Process: oogenesis; vesicle-mediated transport; homologous chromosome movement towards spindle pole during meiosis I; establishment of meiotic spindle localization; protein transport; intracellular transport; multicellular organismal development; polar body extrusion after meiotic divisions; negative regulation of protein catabolic process; response to DNA damage stimulus; negative regulation of apoptosisDisease: Mental Retardation, Autosomal Recessive 47 |
| UniProt Protein Details: | |
| NCBI Summary: | Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.[supplied by OMIM, Apr 2010] |
| UniProt Code: | Q9NZ56 |
| NCBI GenInfo Identifier: | 160707881 |
| NCBI Gene ID: | 56776 |
| NCBI Accession: | NP_064450.3 |
| UniProt Secondary Accession: | Q9NZ56,Q59GF6, Q5VU37, Q9NZ55, B0QZA7 |
| UniProt Related Accession: | Q9NZ56 |
| Molecular Weight: | 180,106 Da |
| NCBI Full Name: | formin-2 |
| NCBI Synonym Full Names: | formin 2 |
| NCBI Official Symbol: | FMN2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | formin-2 |
| UniProt Protein Name: | Formin-2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Formin |
| UniProt Gene Name: | FMN2 |
| UniProt Entry Name: | FMN2_HUMAN |
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