Name: FLT3LG Antibody (PACO21788)
SKU: PACO21788
Availability: OutOfStock

Antibody Name:	FLT3LG Antibody (PACO21788)
Antibody SKU:	PACO21788
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human Flt3 ligand.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Savvides S.N., Nat. Struct. Biol. 7:486-491(2000).
Clonality:	Polyclonal
Conjugate:	Non-conjugated

Western blot analysis of extracts from Jurkat cells, using Flt3 ligand antibody.

Synonyms:

SL cytokine [Precursor]; Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L; FLT3LG

UniProt Protein Function:	FLT3LG: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Cytokine; Ligand, receptor tyrosine kinase; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: extracellular space; membrane; integral to membrane Molecular Function:protein homodimerization activity; cytokine activity; receptor tyrosine kinase binding; receptor binding Biological Process: regulation of myeloid dendritic cell activation; positive regulation of natural killer cell differentiation; lymphocyte differentiation; embryonic hemopoiesis; positive regulation of cell proliferation; positive regulation of protein amino acid phosphorylation; signal transduction; positive regulation of myoblast differentiation
NCBI Summary:	Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
UniProt Code:	P49771
NCBI GenInfo Identifier:	1706818
NCBI Gene ID:	2323
NCBI Accession:	P49771.1
UniProt Secondary Accession:	P49771,Q05C96, A0AVC2, B9EGH2,
UniProt Related Accession:	P49771
Molecular Weight:	approximately 150 kDa
NCBI Full Name:	Fms-related tyrosine kinase 3 ligand
NCBI Synonym Full Names:	fms-related tyrosine kinase 3 ligand
NCBI Official Symbol:	FLT3LG
NCBI Official Synonym Symbols:	FL; FLT3L
NCBI Protein Information:	fms-related tyrosine kinase 3 ligand; flt3 ligand
UniProt Protein Name:	Fms-related tyrosine kinase 3 ligand
UniProt Synonym Protein Names:	SL cytokine
Protein Family:	Receptor-type tyrosine-protein kinase
UniProt Gene Name:	FLT3LG
UniProt Entry Name:	FLT3L_HUMAN

Antibodies	ELISA Kits
FLT3LG Antibody (PACO00811)	Human FLT3L / FMS Like Tyrosine Kinase 3 Ligand ELISA Kit
FLT3LG Antibody (PACO02184)	Human Flt3L (FMS Like Tyrosine Kinase 3 Ligand) CLIA Kit (HUES00073)
	Human Flt3L (FMS Like Tyrosine Kinase 3 Ligand) ELISA Kit (HUES01362)
	Human Fms-related tyrosine kinase 3 ligand (FLT3LG) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)