FKBP2 Polyclonal Antibody
- SKU:
- CAB21404
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | FKBP2 Polyclonal Antibody |
| Product Code: | CAB21404 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Endoplasmic reticulum membrane, Peripheral membrane protein |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-142 of human FKBP2 (NP_004461.2). |
| Sequence: | ATGAE GKRKL QIGVK KRVDH CPIKS RKGDV LHMHY TGKLE DGTEF DSSLP QNQPF VFSLG TGQVI KGWDQ GLLGM CEGEK RKLVI PSELG YGERG APPKI PGGAT LVFEV ELLKI ERRTE L |
| Synonyms: | FKBP13, PPIase, FKBP-13 |
| Calculated MW: | 16kDa |
| Observed MW: | Refer to figures |
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