FIZ1 Antibody (PACO61430)
- SKU:
- PACO61430
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FIZ1 Antibody (PACO61430) |
| Antibody SKU: | PACO61430 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Flt3-interacting zinc finger protein 1 protein (252-410AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: 293 whole cell lysate. All lanes: FIZ1 antibody at 4.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa. |
 | IHC image of PACO61430 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity). |
| Synonyms: | Flt3-interacting zinc finger protein 1, Zinc finger protein 798, FIZ1, ZNF798 |
| UniProt Protein Function: | FIZ1: May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.42Cellular Component: cytoplasm; nucleusMolecular Function: receptor tyrosine kinase binding |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96SL8 |
| NCBI GenInfo Identifier: | 296434506 |
| NCBI Gene ID: | 84922 |
| NCBI Accession: | Q96SL8.2 |
| UniProt Secondary Accession: | Q96SL8,Q6ZMJ7, A2RU72 |
| UniProt Related Accession: | Q96SL8 |
| Molecular Weight: | 51,996 Da |
| NCBI Full Name: | Flt3-interacting zinc finger protein 1 |
| NCBI Synonym Full Names: | FLT3 interacting zinc finger 1 |
| NCBI Official Symbol: | FIZ1 |
| NCBI Official Synonym Symbols: | ZNF798 |
| NCBI Protein Information: | flt3-interacting zinc finger protein 1 |
| UniProt Protein Name: | Flt3-interacting zinc finger protein 1 |
| UniProt Synonym Protein Names: | Zinc finger protein 798 |
| Protein Family: | Flt3-interacting zinc finger protein |
| UniProt Gene Name: | FIZ1 |
| UniProt Entry Name: | FIZ1_HUMAN |
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