Description
Product Name: | FITC Anti-Human MPO Antibody [ABT-101007] |
Product Code: | AGEL3500 |
Size: | 20 Tests, 100 Tests, 200 Tests |
Clone No: | ABT-101007 |
Synonyms: | Myeloperoxidase |
Reactivity: | Human |
Host Species: | Mouse |
Applications: | ICFCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | FITC Mouse IgG1, κ Isotype Control [MOPC-21] |
Conjugation: | FITC |
Applications: | ICFCM |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Fluorescent Label: | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Shipping: | Biological ice pack at 4°C |
Form: | Liquid |
Gene ID: | 4353 |
Swissprot: | P05164 |
Background Information: | Myeloperoxidase (MPO) is a heterotetrameric protein consisting of two 60 kD heavy units and two 12 kD light units. A lysosomal enzyme, MPO is able to catalyze the production of hypochlorous acid, a potent microbicidal agent, from hydrogen peroxide and chloride anion during the neutrophil respiratory burst. MPO is a major enzyme involved in the inflammatory responses of polymorphonuclear leucocytes. MPO is localized to the azurophilic granules of mature granulocytes and monocytes and is also expressed in some acute myeloid leukemia cells. |