FILIP1 Antibody (PACO48674)
- SKU:
- PACO48674
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FILIP1 Antibody (PACO48674) |
| Antibody SKU: | PACO48674 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Filamin-A-interacting protein 1 protein (957-1192AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO48674 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO48674 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A. |
| Synonyms: | Filamin-A-interacting protein 1 (FILIP), FILIP1, KIAA1275 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016] |
| UniProt Code: | Q7Z7B0 |
| NCBI GenInfo Identifier: | 585420407 |
| NCBI Gene ID: | 27145 |
| NCBI Accession: | NP_001276916.1 |
| UniProt Secondary Accession: | Q7Z7B0 |
| UniProt Related Accession: | Q7Z7B0 |
| Molecular Weight: | |
| NCBI Full Name: | filamin-A-interacting protein 1 isoform 1 |
| NCBI Synonym Full Names: | filamin A interacting protein 1 |
| NCBI Official Symbol: | FILIP1 |
| NCBI Official Synonym Symbols: | FILIP |
| NCBI Protein Information: | filamin-A-interacting protein 1 |
| UniProt Protein Name: | Filamin-A-interacting protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | FILIP1 |
| UniProt Entry Name: | FLIP1_HUMAN |
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