Fibronectin Monoclonal Antibody
- SKU:
- CAB23830
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | Fibronectin Monoclonal Antibody |
| Product Code: | CAB23830 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61164 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HUVEC, U-87MG |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 394-614 of human Fibronectin(NP_997647.2). |
| Sequence: | QDQKY SFCTD HTVLV QTRGG NSNGA LCHFP FLYNN HNYTD CTSEG RRDNM KWCGT TQNYD ADQKF GFCPM AAHEE ICTTN EGVMY RIGDQ WDKQH DMGHM MRCTC VGNGR GEWTC IAYSQ LRDQC IVDDI TYNVN DTFHK RHEEG HMLNC TCFGQ GRGRW KCDPV DQCQD SETGT FYQIG DSWEK YVHGV RYQCY CYGRG IGEWH CQPLQ TYPSS SGPVE V |
| Synonyms: | FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, fibronectin |
| Calculated MW: | 71-73kDa/221-272kDa |
| Observed MW: | 272kDa |
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