FGD6 Antibody (PACO37114)
- SKU:
- PACO37114
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FGD6 Antibody (PACO37114) |
| Antibody SKU: | PACO37114 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human FYVE, RhoGEF and PH domain-containing protein 6 protein (1138-1352AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: K562 whole cell lysate. All lanes: FGD6 antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 161, 155 kDa. Observed band size: 161 kDa. |
 | Immunocytochemistry analysis of human adrenal gland tissue using PACO37114 at dilution of 1:100. |
 | Immunocytochemistry analysis of human brain tissue using PACO37114 at dilution of 1:100. |
| Background: | May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape. |
| Synonyms: | FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24), FGD6, KIAA1362 ZFYVE24 |
| UniProt Protein Function: | FGD6: May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs; GEFs, Rac/RhoChromosomal Location of Human Ortholog: 12q22Cellular Component: cytoplasm; Golgi apparatus; lamellipodium; ruffleMolecular Function: guanyl-nucleotide exchange factor activity; small GTPase bindingBiological Process: actin cytoskeleton organization and biogenesis; cytoskeleton organization and biogenesis; filopodium formation; regulation of cell shape; regulation of GTPase activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6ZV73 |
| NCBI GenInfo Identifier: | 61213484 |
| NCBI Gene ID: | 55785 |
| NCBI Accession: | Q6ZV73.2 |
| UniProt Secondary Accession: | Q6ZV73,Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5 |
| UniProt Related Accession: | Q6ZV73 |
| Molecular Weight: | 154,465 Da |
| NCBI Full Name: | FYVE, RhoGEF and PH domain-containing protein 6 |
| NCBI Synonym Full Names: | FYVE, RhoGEF and PH domain containing 6 |
| NCBI Official Symbol: | FGD6 |
| NCBI Official Synonym Symbols: | ZFYVE24 |
| NCBI Protein Information: | FYVE, RhoGEF and PH domain-containing protein 6 |
| UniProt Protein Name: | FYVE, RhoGEF and PH domain-containing protein 6 |
| UniProt Synonym Protein Names: | Zinc finger FYVE domain-containing protein 24 |
| Protein Family: | FYVE, RhoGEF and PH domain-containing protein |
| UniProt Gene Name: | FGD6 |
| UniProt Entry Name: | FGD6_HUMAN |
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