Description
| Antibody Name: | FGD3 Antibody (PACO09281) |
| Antibody SKU: | PACO09281 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human FGD3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | FYVE, RhoGEF and PH domain containing 3;FGD3;FLJ00004;MGC117260;ZFYVE5 ; |
| UniProt Protein Function: | FGD3: Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs; GEFs, Rac/RhoChromosomal Location of Human Ortholog: -Cellular Component: cytoplasm; cytosol; Golgi apparatus; lamellipodium; ruffleMolecular Function: guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; small GTPase bindingBiological Process: actin cytoskeleton organization and biogenesis; cytoskeleton organization and biogenesis; filopodium formation; positive regulation of apoptosis; regulation of cell shape; regulation of GTPase activity; regulation of small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5JSP0 |
| NCBI GenInfo Identifier: | 61213216 |
| NCBI Gene ID: | 89846 |
| NCBI Accession: | Q5JSP0.1 |
| UniProt Secondary Accession: | Q5JSP0,Q4VX84, Q7Z7D9, Q8N5G1, F8W7P2 |
| UniProt Related Accession: | Q5JSP0 |
| Molecular Weight: | 79,273 Da |
| NCBI Full Name: | FYVE, RhoGEF and PH domain-containing protein 3 |
| NCBI Synonym Full Names: | FYVE, RhoGEF and PH domain containing 3 |
| NCBI Official Symbol: | FGD3 |
| NCBI Official Synonym Symbols: | ZFYVE5 |
| NCBI Protein Information: | FYVE, RhoGEF and PH domain-containing protein 3 |
| UniProt Protein Name: | FYVE, RhoGEF and PH domain-containing protein 3 |
| UniProt Synonym Protein Names: | Zinc finger FYVE domain-containing protein 5 |
| Protein Family: | FYVE, RhoGEF and PH domain-containing protein |
| UniProt Gene Name: | FGD3 |
| UniProt Entry Name: | FGD3_HUMAN |