Description
Product Name: | Ferritin Light Chain Polyclonal Antibody |
Product Code: | CAB21758 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:200-1:500, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | RAW264.7, Mouse ovary |
Cellular Location: | cytoplasm, cytosol, extracellular exosome, extracellular region |
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human Ferritin Light Chain (NP_000137.2). |
Sequence: | MSSQI RQNYS TDVEA AVNSL VNLYL QASYT YLSLG FYFDR DDVAL EGVSH FFREL AEEKR EGYER LLKMQ NQRGG RALFQ DIKKP AEDEW GKTPD AMKAA MALEK KLNQA LLDLH ALGSA RTDPH LCDFL ETHFL DEEVK LIKKM GDHLT NLHRL GGPEA GLGEY LFERL TLKHD |
Synonyms: | LFTD, NBIA3 |
Calculated MW: | 20kDa |
Observed MW: | 18-20kDa |