Ferritin Heavy Chain Monoclonal Antibody
- SKU:
- CAB22439
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Description
| Product Name: | Ferritin Heavy Chain Monoclonal Antibody |
| Product Code: | CAB22439 |
| Reactivity: | Human |
| Applications: | Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC2665 |
| Reactivity: | Human |
| Tested Applications: | IHC-P, ELISA |
| Key Applications: | Immunohistochemistry |
| Recommended Dilution: | IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | cytoplasm, cytosol, extracellular exosome, extracellular region, nucleus |
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 84-183 of human Ferritin Heavy Chain (P02794). |
| Sequence: | QDIKK PDCDD WESGL NAMEC ALHLE KNVNQ SLLEL HKLAT DKNDP HLCDF IETHY LNEQV KAIKE LGDHV TNLRK MGAPE SGLAE YLFDK HTLGD SDNES |
| Synonyms: | FHC, FTH, HFE5, PLIF, FTHL6, PIG15 |
| Calculated MW: | 21kDa |
| Observed MW: | Refer to figures |
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