FERD3L Antibody (PACO39622)
- SKU:
- PACO39622
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FERD3L Antibody (PACO39622) |
| Antibody SKU: | PACO39622 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Fer3-like protein (1-167AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39622 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO39622 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins. |
| Synonyms: | Fer3-like protein (Basic helix-loop-helix protein N-twist) (Class A basic helix-loop-helix protein 31) (bHLHa31) (Nephew of atonal 3) (Neuronal twist), FERD3L, BHLHA31 NATO3 NTWIST |
| UniProt Protein Function: | FERD3L: Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 7p21.1Cellular Component: nucleusMolecular Function: protein dimerization activity; DNA bindingBiological Process: floor plate development; regulation of neurogenesis; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; cell development |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96RJ6 |
| NCBI GenInfo Identifier: | 23097242 |
| NCBI Gene ID: | 222894 |
| NCBI Accession: | NP_690862 |
| UniProt Secondary Accession: | Q96RJ6,Q495K0 |
| UniProt Related Accession: | Q96RJ6 |
| Molecular Weight: | 19,017 Da |
| NCBI Full Name: | fer3-like protein |
| NCBI Synonym Full Names: | Fer3-like bHLH transcription factor |
| NCBI Official Symbol: | FERD3L |
| NCBI Official Synonym Symbols: | NATO3; NTWIST; N-TWIST; bHLHa31 |
| NCBI Protein Information: | fer3-like protein |
| UniProt Protein Name: | Fer3-like protein |
| UniProt Synonym Protein Names: | Basic helix-loop-helix protein N-twist; Class A basic helix-loop-helix protein 31; bHLHa31; Nephew of atonal 3; Neuronal twist |
| Protein Family: | Fer3-like protein |
| UniProt Gene Name: | FERD3L |
| UniProt Entry Name: | FER3L_HUMAN |
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