Description
| Product Name: | FCGRT/FCRN Monoclonal Antibody |
| Product Code: | CAB23161 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59051 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2 |
| Cellular Location: | Cell membrane, Endosome membrane |
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-290 human FCGRT/FCRN (NP_004098.1). |
| Sequence: | HLSLL YHLTA VSSPA PGTPA FWVSG WLGPQ QYLSY NSLRG EAEPC GAWVW ENQVS WYWEK ETTDL RIKEK LFLEA FKALG GKGPY TLQGL LGCEL GPDNT SVPTA KFALN GEEFM NFDLK QGTWG GDWPE ALAIS QRWQQ QDKAA NKELT FLLFS CPHRL REHLE RGRGN LEWKE PPSMR LKARP SSPGF SVLTC SAFSF YPPEL QLRFL RNGLA AGTGQ GDFGP NSDGS FHASS SLTVK SGDEH HYCCI VQHAG LAQPL RVEL |
| Synonyms: | FCRN, FcgammaRn, IgG Fc fragment receptor transporter alpha chain |
| Calculated MW: | 40kDa |
| Observed MW: | 40-43kDa |
