FCAR Monoclonal Antibody
- SKU:
- CAB23280
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- FC
Description
| Product Name: | FCAR Monoclonal Antibody |
| Product Code: | CAB23280 |
| Reactivity: | Human |
| Applications: | Western blotting, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59840 |
| Reactivity: | Human |
| Tested Applications: | WB, FC, ELISA |
| Key Applications: | Western blotting, Flow Cytometry |
| Recommended Dilution: | WB 1:1000-1:5000, FC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | CD89-293T trasfected |
| Cellular Location: | Cell membrane, Secreted, Single-pass type I membrane protein |
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Immunogen: | Recombinant protein of human FCAR. |
| Sequence: | Email for sequence |
| Synonyms: | CD89, FcalphaR, FcalphaRI, CTB-61M7.2 |
| Calculated MW: | 32kDa |
| Observed MW: | 37-75kDa |
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