Fbxw10 Antibody (PACO49206)
- SKU:
- PACO49206
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Fbxw10 Antibody (PACO49206) |
| Antibody SKU: | PACO49206 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse F-box/WD repeat-containing protein 10 protein (701-1030AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 (By similarity). |
| Synonyms: | F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10), Fbxw10 |
| UniProt Protein Function: | FBXW10: Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 11|11 B2Molecular Function: ubiquitin-protein ligase activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5SUS0 |
| NCBI GenInfo Identifier: | 81910136 |
| NCBI Gene ID: | 213980 |
| NCBI Accession: | Q5SUS0.1 |
| UniProt Secondary Accession: | Q5SUS0,Q5U4G1 |
| UniProt Related Accession: | Q5SUS0 |
| Molecular Weight: | 53.16 kDa |
| NCBI Full Name: | F-box/WD repeat-containing protein 10 |
| NCBI Synonym Full Names: | F-box and WD-40 domain protein 10 |
| NCBI Official Symbol: | Fbxw10 |
| NCBI Official Synonym Symbols: | HREP; Fbw10; SM25H2; SM2SH2 |
| NCBI Protein Information: | F-box/WD repeat-containing protein 10 |
| UniProt Protein Name: | F-box/WD repeat-containing protein 10 |
| UniProt Synonym Protein Names: | F-box and WD-40 domain-containing protein 10 |
| Protein Family: | F-box/WD repeat-containing protein |
| UniProt Gene Name: | Fbxw10 |
| UniProt Entry Name: |
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