Description
Antibody Name: | FBXO44 Antibody (PACO41074) |
Antibody SKU: | PACO41074 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human F-box only protein 44 protein (1-224AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
Synonyms: | F-box only protein 44 (F-box protein FBX30) (F-box/G-domain protein 3), FBXO44, FBG3 FBX30 FBX44 FBX6A FBXO6A |
UniProt Protein Function: | FBXO44: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 1p36.22Cellular Component: SCF ubiquitin ligase complexMolecular Function: protein binding |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Feb 2015] |
UniProt Code: | Q9H4M3 |
NCBI GenInfo Identifier: | 61252661 |
NCBI Gene ID: | 93611 |
NCBI Accession: | Q9H4M3.3 |
UniProt Secondary Accession: | Q9H4M3,Q5TGX2, Q5TGX4, Q5TGX5, Q68DJ9, Q8WWY2, B3KNZ2 B7Z743 |
UniProt Related Accession: | Q9H4M3 |
Molecular Weight: | 25,698 Da |
NCBI Full Name: | F-box only protein 44 |
NCBI Synonym Full Names: | F-box protein 44 |
NCBI Official Symbol: | FBXO44 |
NCBI Official Synonym Symbols: | FBG3; FBX30; FBX6A; Fbx44; Fbxo6a |
NCBI Protein Information: | F-box only protein 44 |
UniProt Protein Name: | F-box only protein 44 |
UniProt Synonym Protein Names: | F-box protein FBX30; F-box/G-domain protein 3 |
Protein Family: | F-box only protein |
UniProt Gene Name: | FBXO44 |
UniProt Entry Name: | FBX44_HUMAN |