FBXO40 Antibody (PACO41778)
- SKU:
- PACO41778
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FBXO40 Antibody (PACO41778) |
| Antibody SKU: | PACO41778 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human F-box only protein 40 protein (201-500AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO41778 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO41778 at dilution of 1:100. |
| Background: | Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis. |
| Synonyms: | F-box only protein 40 (Muscle disease-related protein), FBXO40, FBX40 KIAA1195 |
| UniProt Protein Function: | FBXO40: Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.Protein type: Unknown functionChromosomal Location of Human Ortholog: 3q13.33Cellular Component: cytoplasmMolecular Function: zinc ion bindingBiological Process: muscle cell differentiation; protein ubiquitination |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9UH90 |
| NCBI GenInfo Identifier: | 156546888 |
| NCBI Gene ID: | 51725 |
| NCBI Accession: | NP_057382.2 |
| UniProt Secondary Accession: | Q9UH90,Q32M70, Q9ULM5, B2RAX7 |
| UniProt Related Accession: | Q9UH90 |
| Molecular Weight: | 79,782 Da |
| NCBI Full Name: | F-box only protein 40 |
| NCBI Synonym Full Names: | F-box protein 40 |
| NCBI Official Symbol: | FBXO40 |
| NCBI Official Synonym Symbols: | FBX40 |
| NCBI Protein Information: | F-box only protein 40 |
| UniProt Protein Name: | F-box only protein 40 |
| UniProt Synonym Protein Names: | Muscle disease-related protein |
| Protein Family: | F-box only protein |
| UniProt Gene Name: | FBXO40 |
| UniProt Entry Name: | FBX40_HUMAN |
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