FBXO36 Antibody (PACO64235)
- SKU:
- PACO64235
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FBXO36 Antibody (PACO64235) |
| Antibody SKU: | PACO64235 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | IF:1:100-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human F-box only protein 36 protein (1-188AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of SH-SY5Y cells with PACO64235 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
| Synonyms: | F-box only protein 36, FBXO36, FBX36 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the F-box protein family, such as FBXO36, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8NEA4 |
| NCBI GenInfo Identifier: | 21707538 |
| NCBI Gene ID: | 130888 |
| NCBI Accession: | BC033935.1 |
| UniProt Secondary Accession: | Q8NEA4 |
| UniProt Related Accession: | Q8NEA4 |
| Molecular Weight: | |
| NCBI Full Name: | Homo sapiens F-box protein 36, mRNA |
| NCBI Synonym Full Names: | F-box protein 36 |
| NCBI Official Symbol: | FBXO36 |
| NCBI Official Synonym Symbols: | Fbx36 |
| NCBI Protein Information: | F-box only protein 36 |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | F-box only protein |
| UniProt Gene Name: | |
| UniProt Entry Name: |
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