FBXO30 Antibody (PACO39186)
- SKU:
- PACO39186
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FBXO30 Antibody (PACO39186) |
| Antibody SKU: | PACO39186 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human F-box only protein 30 protein (201-500AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: FBXO30 antibody at 10µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 83 kDa. Observed band size: 83 kDa. |
 | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO39186 at dilution of 1:100. |
| Background: | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation. |
| Synonyms: | F-box only protein 30, FBXO30, FBX30 |
| UniProt Protein Function: | FBXO30: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.Protein type: Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 6q24Molecular Function: zinc ion bindingBiological Process: protein ubiquitination |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TB52 |
| NCBI GenInfo Identifier: | 34577055 |
| NCBI Gene ID: | 84085 |
| NCBI Accession: | NP_115521.3 |
| UniProt Secondary Accession: | Q8TB52,Q9BXZ7 |
| UniProt Related Accession: | Q8TB52 |
| Molecular Weight: | |
| NCBI Full Name: | F-box only protein 30 |
| NCBI Synonym Full Names: | F-box protein 30 |
| NCBI Official Symbol: | FBXO30 |
| NCBI Official Synonym Symbols: | Fbx30 |
| NCBI Protein Information: | F-box only protein 30 |
| UniProt Protein Name: | F-box only protein 30 |
| UniProt Synonym Protein Names: | |
| Protein Family: | F-box only protein |
| UniProt Gene Name: | FBXO30 |
| UniProt Entry Name: | FBX30_HUMAN |
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