Description
| Antibody Name: | FBXL8 Antibody (PACO09249) |
| Antibody SKU: | PACO09249 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human FBXL8 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | F-box and leucine-rich repeat protein 8;FBXL8;FBL8;FLJ11278;MGC19959 ; |
| UniProt Protein Function: | FBXL8: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.Chromosomal Location of Human Ortholog: 16q22.1Cellular Component: cytosolMolecular Function: protein binding; ubiquitin-protein ligase activityBiological Process: protein polyubiquitination |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96CD0 |
| NCBI GenInfo Identifier: | 38257737 |
| NCBI Gene ID: | 55336 |
| NCBI Accession: | Q96CD0.1 |
| UniProt Secondary Accession: | Q96CD0,Q9NUM0 |
| UniProt Related Accession: | Q96CD0 |
| Molecular Weight: | 40,516 Da |
| NCBI Full Name: | F-box/LRR-repeat protein 8 |
| NCBI Synonym Full Names: | F-box and leucine rich repeat protein 8 |
| NCBI Official Symbol: | FBXL8 |
| NCBI Official Synonym Symbols: | FBL8 |
| NCBI Protein Information: | F-box/LRR-repeat protein 8 |
| UniProt Protein Name: | F-box/LRR-repeat protein 8 |
| UniProt Synonym Protein Names: | F-box and leucine-rich repeat protein 8; F-box protein FBL8 |
| Protein Family: | F-box/LRR-repeat protein |
| UniProt Gene Name: | FBXL8 |
| UniProt Entry Name: | FBXL8_HUMAN |