FBXL19 Antibody (PACO50682)
- SKU:
- PACO50682
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FBXL19 Antibody (PACO50682) |
| Antibody SKU: | PACO50682 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human F-box/LRR-repeat protein 19 protein (4-259AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of A549 cells using PACO50682 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
| Synonyms: | F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19), FBXL19, FBL19 |
| UniProt Protein Function: | FBXL19: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 16p11.2Cellular Component: SCF ubiquitin ligase complexMolecular Function: protein bindingBiological Process: proteasomal ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q6PCT2 |
| NCBI GenInfo Identifier: | 322510127 |
| NCBI Gene ID: | 54620 |
| NCBI Accession: | Q6PCT2.3 |
| UniProt Secondary Accession: | Q6PCT2,Q8N789, Q9NT14, A8MT10 |
| UniProt Related Accession: | Q6PCT2 |
| Molecular Weight: | 72,253 Da |
| NCBI Full Name: | F-box/LRR-repeat protein 19 |
| NCBI Synonym Full Names: | F-box and leucine rich repeat protein 19 |
| NCBI Official Symbol: | FBXL19 |
| NCBI Official Synonym Symbols: | Fbl19; CXXC11; JHDM1C |
| NCBI Protein Information: | F-box/LRR-repeat protein 19 |
| UniProt Protein Name: | F-box/LRR-repeat protein 19 |
| UniProt Synonym Protein Names: | F-box and leucine-rich repeat protein 19 |
| Protein Family: | F-box/LRR-repeat protein |
| UniProt Gene Name: | FBXL19 |
| UniProt Entry Name: | FXL19_HUMAN |
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