FBXL17 Antibody (PACO40702)
- SKU:
- PACO40702
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FBXL17 Antibody (PACO40702) |
| Antibody SKU: | PACO40702 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human F-box/LRR-repeat protein 17 protein (1-303AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO40702 at dilution of 1:100. |
| Background: | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
| Synonyms: | F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13), FBXL17, FBL17 FBX13 FBXO13 |
| UniProt Protein Function: | FBXL17: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 5q21.3 |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9UF56 |
| NCBI GenInfo Identifier: | 229462981 |
| NCBI Gene ID: | 64839 |
| NCBI Accession: | Q9UF56.3 |
| UniProt Secondary Accession: | Q9UF56,A1A4E3 |
| UniProt Related Accession: | Q9UF56 |
| Molecular Weight: | 35,451 Da |
| NCBI Full Name: | F-box/LRR-repeat protein 17 |
| NCBI Synonym Full Names: | F-box and leucine rich repeat protein 17 |
| NCBI Official Symbol: | FBXL17 |
| NCBI Official Synonym Symbols: | Fbl17; Fbx13; FBXO13 |
| NCBI Protein Information: | F-box/LRR-repeat protein 17 |
| UniProt Protein Name: | F-box/LRR-repeat protein 17 |
| UniProt Synonym Protein Names: | F-box and leucine-rich repeat protein 17; F-box only protein 13 |
| Protein Family: | F-box/LRR-repeat protein |
| UniProt Gene Name: | FBXL17 |
| UniProt Entry Name: | FXL17_HUMAN |
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