Fatty Acid Synthase (FASN) Polyclonal Antibody (CAB21398)

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SKU:
CAB21398
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Fatty Acid Synthase (FASN) Polyclonal Antibody
Product Code:CAB21398
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:HeLa, MCF7, Mouse liver, Rat liver
Cellular Location:Cytoplasm, Melanosome

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 2221-2511 of human Fatty Acid Synthase (FASN) (NP_004095.4).
Sequence:SLLVN PEGPT LMRLN SVQSS ERPLF LVHPI EGSTT VFHSL ASRLS IPTYG LQCTR AAPLD SIHSL AAYYI DCIRQ VQPEG PYRVA GYSYG ACVAF EMCSQ LQAQQ SPAPT HNSLF LFDGS PTYVL AYTQS YRAKL TPGCE AEAET EAICF FVQQF TDMEH NRVLE ALLPL KGLEE RVAAA VDLII KSHQG LDRQE LSFAA RSFYY KLRAA EQYTP KAKYH GNVML LRAKT GGAYG EDLGA DYNLS QVCDG KVSVH VIEGD HRTLL EGSGL ESIIS IIHSS LAEPR VSVRE G
Synonyms:FAS, OA-519, SDR27X1
Calculated MW:273kDa
Observed MW:273kDa
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