Fatty Acid Synthase (FASN) Monoclonal Antibody
- SKU:
- CAB21182
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Fatty Acid Synthase (FASN) Monoclonal Antibody |
| Product Code: | CAB21182 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53122 |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293F, HeLa, Rat liver |
| Cellular Location: | Cytoplasm, Cytosol, Extracellular exosome, Glycogen granule, Golgi apparatus, Melanosome, Plasma membrane |
| Customer Validation: | WB(Homo sapiens) |
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2212-2511 of human Fatty Acid Synthase (FASN) (NP_004095.4). |
| Sequence: | QQQTQ LNLRS LLVNP EGPTL MRLNS VQSSE RPLFL VHPIE GSTTV FHSLA SRLSI PTYGL QCTRA APLDS IHSLA AYYID CIRQV QPEGP YRVAG YSYGA CVAFE MCSQL QAQQS PAPTH NSLFL FDGSP TYVLA YTQSY RAKLT PGCEA EAETE AICFF VQQFT DMEHN RVLEA LLPLK GLEER VAAAV DLIIK SHQGL DRQEL SFAAR SFYYK LRAAE QYTPK AKYHG NVMLL RAKTG GAYGE DLGAD YNLSQ VCDGK VSVHV IEGDH RTLLE GSGLE SIISI IHSSL AEPRV SVREG |
| Synonyms: | FAS, OA-519, SDR27X1 |
| Calculated MW: | 273kDa |
| Observed MW: | 273kDa |
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