Description
Product Name: | FASTKD3 Polyclonal Antibody |
Product Code: | CAB7833 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Mitochondrion |
This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human FASTKD3 (NP_076996.2). |
Sequence: | MALIT LRKNL YRLSD FQMHR ALAAL KNKPL NHVHK VVKER LCPWL CSRQP EPFGV KFHHA HCKKF HSKNG NDLHP LGGPV FSQVS DCDRL EQNVK NEESQ MFYRR LSNLT SSEEV LSFIS TMETL PDTMA AGALQ RICEV EKKDG DQGLP KEILE NSIFQ ALCFQ FEKEP SQLSN TSLVT ALQAL ILLHV DPQSS LLLNL VAECQ NRLRK GGMEV RNLCI |
Synonyms: | FASTKD3 |
Calculated MW: | 76kDa |
Observed MW: | Refer to figures |