Description
| Antibody Name: | FARP2 Antibody |
| Antibody SKU: | PACO00805 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the Internal region of human FIR. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | FARP2; KIAA0793; PLEKHC3; FERM; RhoGEF and pleckstrin domain-containing protein 2; FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3 |
| UniProt Protein Function: | FARP2: Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; GEF; GEF, Rac/Rho; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: cytoplasm; cytoskeleton; cytosol Molecular Function:cytoskeletal protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity Biological Process: actin cytoskeleton reorganization; cell adhesion; hair cycle process; neuron remodeling; osteoclast differentiation; positive regulation of GTPase activity; Rac protein signal transduction; regulation of integrin activation; regulation of Rho protein signal transduction |
| UniProt Code: | O94887 |
| NCBI GenInfo Identifier: | 545478372 |
| NCBI Gene ID: | 9855 |
| NCBI Accession: | NP_001269912.1 |
| UniProt Secondary Accession: | O94887,Q53QM5, Q8WU27, Q9UFE7, B7Z6J8, F5GZ84, |
| UniProt Related Accession: | O94887 |
| Molecular Weight: | 119 kDa |
| NCBI Full Name: | FERM, ARHGEF and pleckstrin domain-containing protein 2 isoform b |
| NCBI Synonym Full Names: | FERM, ARH/RhoGEF and pleckstrin domain protein 2 |
| NCBI Official Symbol: | FARP2 |
| NCBI Official Synonym Symbols: | FIR; FRG; PLEKHC3 |
| NCBI Protein Information: | FERM, ARHGEF and pleckstrin domain-containing protein 2; FERM, RhoGEF and pleckstrin domain-containing protein 2 |
| UniProt Protein Name: | FERM, ARHGEF and pleckstrin domain-containing protein 2 |
| UniProt Synonym Protein Names: | FERM domain-including RhoGEF; FIR; FERM, RhoGEF and pleckstrin domain-containing protein 2; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3 |
| UniProt Gene Name: | FARP2 |