FAR2 Antibody (PACO38174)
- SKU:
- PACO38174
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FAR2 Antibody (PACO38174) |
| Antibody SKU: | PACO38174 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Fatty acyl-CoA reductase 2 protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO38174 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO38174 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO38174 at dilution of 1:100. |
| Background: | Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and C18:2 but low activity can be observed with C10-C14 substrates. |
| Synonyms: | Fatty acyl-CoA reductase 2 (EC 1.2.1.84) (Male sterility domain-containing protein 1), FAR2, MLSTD1 |
| UniProt Protein Function: | MLSTD1: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and C18:2 but low activity can be observed with C10-C14 substrates. Belongs to the fatty acyl-CoA reductase family.Protein type: Oxidoreductase; Membrane protein, integral; EC 1.2.1.n2; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12p11.22Cellular Component: peroxisomal membrane; peroxisomal matrix; endoplasmic reticulum membrane; integral to membrane; peroxisomeMolecular Function: long-chain-fatty-acyl-CoA reductase activityBiological Process: cellular lipid metabolic process; ether lipid biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q96K12 |
| NCBI GenInfo Identifier: | 74732166 |
| NCBI Gene ID: | 55711 |
| NCBI Accession: | Q96K12.1 |
| UniProt Secondary Accession: | Q96K12,Q9H0D5, Q9NVW8, F8VV73 |
| UniProt Related Accession: | Q96K12 |
| Molecular Weight: | |
| NCBI Full Name: | Fatty acyl-CoA reductase 2 |
| NCBI Synonym Full Names: | fatty acyl CoA reductase 2 |
| NCBI Official Symbol: | FAR2 |
| NCBI Official Synonym Symbols: | MLSTD1; SDR10E2 |
| NCBI Protein Information: | fatty acyl-CoA reductase 2; male sterility domain-containing protein 1; short chain dehydrogenase/reductase family 10E, member 2 |
| UniProt Protein Name: | Fatty acyl-CoA reductase 2 |
| UniProt Synonym Protein Names: | Male sterility domain-containing protein 1 |
| Protein Family: | Fatty acyl-CoA reductase |
| UniProt Gene Name: | FAR2 |
| UniProt Entry Name: | FACR2_HUMAN |
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