Antibody Name:	FAR2 Antibody (PACO16315)
Antibody SKU:	PACO16315
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:	Human, Mouse
Immunogen:	Fusion protein of human FAR2

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16315(FAR2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
	Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: PACO16315(FAR2 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds.
	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16315(FAR2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).

Background:

This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acid, are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acid, of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22.

Synonyms:

fatty acyl CoA reductase 2

UniProt Protein Function:	MLSTD1: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and C18:2 but low activity can be observed with C10-C14 substrates. Belongs to the fatty acyl-CoA reductase family.Protein type: Oxidoreductase; Membrane protein, integral; EC 1.2.1.n2; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12p11.22Cellular Component: peroxisomal membrane; peroxisomal matrix; endoplasmic reticulum membrane; integral to membrane; peroxisomeMolecular Function: long-chain-fatty-acyl-CoA reductase activityBiological Process: cellular lipid metabolic process; ether lipid biosynthetic process
UniProt Protein Details:
NCBI Summary:	This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012]
UniProt Code:	Q96K12
NCBI GenInfo Identifier:	74732166
NCBI Gene ID:	55711
NCBI Accession:	Q96K12.1
UniProt Secondary Accession:	Q96K12,Q9H0D5, Q9NVW8, F8VV73
UniProt Related Accession:	Q96K12
Molecular Weight:
NCBI Full Name:	Fatty acyl-CoA reductase 2
NCBI Synonym Full Names:	fatty acyl CoA reductase 2
NCBI Official Symbol:	FAR2
NCBI Official Synonym Symbols:	MLSTD1; SDR10E2
NCBI Protein Information:	fatty acyl-CoA reductase 2; male sterility domain-containing protein 1; short chain dehydrogenase/reductase family 10E, member 2
UniProt Protein Name:	Fatty acyl-CoA reductase 2
UniProt Synonym Protein Names:	Male sterility domain-containing protein 1
Protein Family:	Fatty acyl-CoA reductase
UniProt Gene Name:	FAR2
UniProt Entry Name:	FACR2_HUMAN