Description
Product Name: | FAM38A/PIEZO1 Monoclonal Antibody |
Product Code: | CAB23380 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC60118 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | MCF7, Mouse lung |
Cellular Location: | Cell membrane, Cell projection, Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Multi-pass membrane protein, lamellipodium membrane |
Customer Validation: | IHC(Mus musculus) |
The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2199-2429 of human PIEZO1(NP_001136336.2). |
Sequence: | VVGVV NQPID VTVTL KLGGY EPLFT MSAQQ PSIIP FTAQA YEELS RQFDP QPLAM QFISQ YSPED IVTAQ IEGSS GALWR ISPPS RAQMK RELYN GTADI TLRFT WNFQR DLAKG GTVEY ANEKH MLALA PNSTA RRQLA SLLEG TSDQS VVIPN LFPKY IRAPN GPEAN PVKQL QPNEE ADYLG VRIQL RREQG AGATG FLEWW VIELQ ECRTD CNLLP MVIFS DKVSP |
Synonyms: | ER, DHS, Mib, LMPH3, FAM38A, LMPHM6 |
Calculated MW: | 287kDa |
Observed MW: | 287kDa |