FAM13B Antibody (PACO19644)
- SKU:
- PACO19644
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FAM13B Antibody (PACO19644) |
| Antibody SKU: | PACO19644 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human FAM13B |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19644(FAM13B Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19644(FAM13B Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | FAM13B is a 915 amino acid, protein that is encoded by a gene that maps to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Synonyms: | family with sequence similarity 13, member B |
| UniProt Protein Function: | FAM13B: a protein that contains 1 Rho-GAP domain.Protein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 5q31Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: positive regulation of defense response to virus by host; regulation of small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NYF5 |
| NCBI GenInfo Identifier: | 116241292 |
| NCBI Gene ID: | 51306 |
| NCBI Accession: | Q9NYF5.2 |
| UniProt Secondary Accession: | Q9NYF5,Q3ZCR0, Q6PGQ2, Q9P0I7, D3DQB5, G3V0H9 |
| UniProt Related Accession: | Q9NYF5 |
| Molecular Weight: | 90,577 Da |
| NCBI Full Name: | Protein FAM13B |
| NCBI Synonym Full Names: | family with sequence similarity 13 member B |
| NCBI Official Symbol: | FAM13B |
| NCBI Official Synonym Symbols: | N61; KHCHP; C5orf5; FAM13B1; ARHGAP49 |
| NCBI Protein Information: | protein FAM13B |
| UniProt Protein Name: | Protein FAM13B |
| UniProt Synonym Protein Names: | GAP-like protein N61 |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM13B |
| UniProt Entry Name: | FA13B_HUMAN |
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