FAK Polyclonal Antibody (CAB21738)
- SKU:
- CAB21738
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | FAK Polyclonal Antibody |
| Product Code: | CAB21738 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC-P, IF/ICC, ELISA |
| Key Applications: | Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Cellular Location: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein, cell cortex, centrosome, cytoskeleton, focal adhesion, microtubule organizing center |
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 734-834 of human FAK (NP_722560.1). |
| Sequence: | QHMVQ TNHYQ VSGYP GSHGI TAMAG SIYPG QASLL DQTDS WNHRP QEIAM WQPNV EDSTV LDLRG IGQVL PTHLM EERLI RQQQE MEEDQ RWLEK EERFL K |
| Synonyms: | FAK, FADK, FAK1, FRNK, FADK 1, PPP1R71, p125FAK, pp125FAK |
| Calculated MW: | 119kDa |
| Observed MW: | Refer to figures |
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