Description
Product Name: | FADS2 Polyclonal Antibody |
Product Code: | CAB24354 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | Hep G2 |
Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FADS2 (NP_004256.1). |
Sequence: | MGKGG NQGEG AAERE VSVPT FSWEE IQKHN LRTDR WLVID RKVYN ITKWS IQHPG GQRVI GHYAG EDATD AFRAF HPDLE FVGKF LKPLL IGELA PEEPS |
Synonyms: | D6D, DES6, TU13, FADSD6, LLCDL2, SLL0262 |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |