FABP4 Monoclonal Antibody [P3F4AT] (CPAB0533)
![FABP4 Monoclonal Antibody [P3F4AT] (CPAB0533)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58754/63936/fabp4-monoclonal-antibody-p3f4at-cpab0533__20060__17937.1706535206.jpg?c=1 "FABP4 Monoclonal Antibody [P3F4AT] (CPAB0533)")
- SKU:
- CPAB0533
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- P3F4AT
- Applications:
- WB
- Applications:
- ELISA
![FABP4 Monoclonal Antibody [P3F4AT] (CPAB0533)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58754/63936/fabp4-monoclonal-antibody-p3f4at-cpab0533__20060__17937.1706535206.jpg?c=1&imbypass=on "FABP4 Monoclonal Antibody [P3F4AT] (CPAB0533)")
Description
system_update_alt Datasheet
| Product Name: | FABP4 Antibody |
| Product Sku: | CPAB0533 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human FABP4 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human FABP4 amino acids 1-132 purified from Ecoli. |
| Clone: | P3F4AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | FABP4 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG1 |
| Background: | Adipocyte fatty acid binding protein FABP4 is a 15 kDa member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids) in an internal cavity. FABP4 is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. In mice, targeted mutations in FABP4 provide significant protection from hyperinsulinemia and insulin resistance in the context of both dietary and genetic obesity. Adipocytes obtained from FABP4-deficient mice also have reduced efficiency of ipolysis in vitro and in vivo, and these mice exhibited moderately improved systemic dyslipidemia. Recent studies also demonstrated FABP4 expression in macrophages upon differentiation and activation. |
| Synonyms: | Fatty acid-binding protein adipocyte, AFABP, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, ALBP, A-FABP, FABP4. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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