FAAP20 Antibody (PACO46674)
- SKU:
- PACO46674
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FAAP20 Antibody (PACO46674) |
| Antibody SKU: | PACO46674 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Fanconi anemia core complex-associated protein 20 protein (14-179AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO46674 at dilution of 1:100. |
| Background: | Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1. |
| Synonyms: | Fanconi anemia core complex-associated protein 20 (FANCA-associated protein of 20 kDa) (Fanconi anemia-associated protein of 20 kDa), FAAP20, C1orf86 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6NZ36 |
| NCBI GenInfo Identifier: | 123701942 |
| NCBI Gene ID: | 199990 |
| NCBI Accession: | NP_872339 |
| UniProt Secondary Accession: | Q6NZ36 |
| UniProt Related Accession: | Q6NZ36 |
| Molecular Weight: | 19kDa |
| NCBI Full Name: | Fanconi anemia core complex-associated protein 20 isoform 2 |
| NCBI Synonym Full Names: | FA core complex associated protein 20 |
| NCBI Official Symbol: | FAAP20 |
| NCBI Official Synonym Symbols: | FP7162; C1orf86 |
| NCBI Protein Information: | Fanconi anemia core complex-associated protein 20 |
| UniProt Protein Name: | Fanconi anemia-associated protein of 20 kDa |
| UniProt Synonym Protein Names: | |
| Protein Family: | Fanconi anemia core complex-associated protein |
| UniProt Gene Name: | FAAP20 |
| UniProt Entry Name: | FAP20_HUMAN |
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