F12 Antibody (PACO51486)
- SKU:
- PACO51486
- Product Type:
- Antibody
- Reactivity:
- Porcine
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | F12 Antibody (PACO51486) |
| Antibody SKU: | PACO51486 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Pig |
| Immunogen: | Recombinant Pig Coagulation factor XII protein (20-371AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity). |
| Synonyms: | Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Coagulation factor XIIa light chain], F12 |
| UniProt Protein Function: | Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. |
| UniProt Code: | O97507 |
| NCBI GenInfo Identifier: | 47523558 |
| NCBI Gene ID: | 397474 |
| NCBI Accession: | NP_999407.1 |
| UniProt Related Accession: | O97507 |
| Molecular Weight: | 68,012 Da |
| NCBI Full Name: | coagulation factor XII |
| NCBI Official Symbol: | F12 |
| NCBI Official Synonym Symbols: | FXII |
| NCBI Protein Information: | coagulation factor XII |
| UniProt Protein Name: | Coagulation factor XII |
| UniProt Synonym Protein Names: | Hageman factor; HAF |
| Protein Family: | Coagulation factor |
| UniProt Gene Name: | F12 |
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