Description
Product Name: | EZH2/KMT6 Polyclonal Antibody |
Product Code: | CAB21997 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | MCF7, Neuro-2a |
Cellular Location: | cytoplasm, nucleoplasm, nucleus, pronucleus |
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 158-261 of EZH2/KMT6 (NP_001190176.1). |
Sequence: | HGDRE CGFIN DEIFV ELVNA LGQYN DDDDD DDGDD PEERE EKQKD LEDHR DDKES RPPRK FPSDK IFEAI SSMFP DKGTA EELKE KYKEL TEQQL PGALP PECT |
Synonyms: | WVS, ENX1, KMT6, WVS2, ENX-1, EZH2b, KMT6A |
Calculated MW: | 85kDa |
Observed MW: | 98kDa |