Description
| Product Name: | EXT1 Polyclonal Antibody |
| Product Code: | CAB24353 |
| Reactivity: | Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat spleen |
| Cellular Location: | Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass type II membrane protein |
This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human EXT1(NP_000118.2). |
| Sequence: | HGKDW QKHKD SRCDR DNTEY EKYDY REMLH NATFC LVPRG RRLGS FRFLE ALQAA CVPVM LSNGW ELPFS EVINW NQAAV IGDER LLLQI PSTIR SIHQD K |
| Synonyms: | EXT, LGS, TTV, LGCR, TRPS2 |
| Calculated MW: | 86kDa |
| Observed MW: | 86kDa |