Exendin-4 Antibody (PACO19630)
- SKU:
- PACO19630
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Exendin-4 Antibody (PACO19630) |
| Antibody SKU: | PACO19630 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | ELISA:1:1000-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of Heloderma suspectum Exendin 4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Exendin 4 is a 39 amino acid, peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle. |
| Synonyms: | Exendin 4 |
| UniProt Protein Function: | Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P26349 |
| NCBI GenInfo Identifier: | 2851623 |
| NCBI Gene ID: | |
| NCBI Accession: | P26349.2 |
| UniProt Secondary Accession: | P26349 |
| UniProt Related Accession: | P26349 |
| Molecular Weight: | |
| NCBI Full Name: | Exendin-4 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Exendin-4 |
| UniProt Synonym Protein Names: | INN: Exenatide |
| Protein Family: | |
| UniProt Gene Name: | |
| UniProt Entry Name: | EXE4_HELSU |
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