EXD2 Antibody (PACO47082)
- SKU:
- PACO47082
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EXD2 Antibody (PACO47082) |
| Antibody SKU: | PACO47082 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Exonuclease 3'-5' domain-containing protein 2 protein (137-245AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Mouse brain tissue, Mouse stomach tissue. All lanes: EXD2 antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 71, 57 kDa. Observed band size: 71 kDa.. |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO47082 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO47082 at dilution of 1:100. |
| Background: | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
| Synonyms: | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2), EXD2, C14orf114 EXDL2 |
| UniProt Protein Function: | EXDL2: Belongs to the EXD2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 14q24.1Cellular Component: cytoplasm; nucleusMolecular Function: nucleic acid binding; 3'-5' exonuclease activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NVH0 |
| NCBI GenInfo Identifier: | 410516875 |
| NCBI Gene ID: | 55218 |
| NCBI Accession: | Q9NVH0.2 |
| UniProt Secondary Accession: | Q9NVH0 |
| UniProt Related Accession: | Q9NVH0 |
| Molecular Weight: | 70 kDa |
| NCBI Full Name: | Exonuclease 3'-5' domain-containing protein 2 |
| NCBI Synonym Full Names: | exonuclease 3'-5' domain containing 2 |
| NCBI Official Symbol: | EXD2 |
| NCBI Official Synonym Symbols: | EXDL2; C14orf114 |
| NCBI Protein Information: | exonuclease 3'-5' domain-containing protein 2 |
| UniProt Protein Name: | Exonuclease 3'-5' domain-containing protein 2 |
| UniProt Synonym Protein Names: | Exonuclease 3'-5' domain-like-containing protein 2 |
| Protein Family: | Exonuclease 3'-5' domain-containing protein |
| UniProt Gene Name: | EXD2 |
| UniProt Entry Name: | EXD2_HUMAN |
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