UniProt Protein Function: | ETFDH: Accepts electrons from ETF and reduces ubiquinone. Defects in ETFDH are the cause of glutaric aciduria type 2C (GA2C). GA2C is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Belongs to the ETF-QO/FixC family.Protein type: EC 1.5.5.1; Membrane protein, integral; Mitochondrial; Oxidoreductase |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P55931 |
NCBI GenInfo Identifier: | 298286807 |
NCBI Gene ID: | 100515785 |
NCBI Accession: | P55931.2 |
UniProt Secondary Accession: | P55931 |
UniProt Related Accession: | P55931, AAB30031 |
Molecular Weight: | 80.8kD |
NCBI Full Name: | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | ETFDH |
NCBI Official Synonym Symbols: | ETF-QO |
NCBI Protein Information: | electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial |
UniProt Protein Name: | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial |
UniProt Synonym Protein Names: | Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase |
Protein Family: | Electron transfer flavoprotein-ubiquinone oxidoreductase |
UniProt Gene Name: | ETFDH |
UniProt Entry Name: | |