ESR1 Monoclonal Antibody [LSERASC1] (CPAB0580)
![ESR1 Monoclonal Antibody [LSERASC1] (CPAB0580)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58801/63983/esr1-monoclonal-antibody-lserasc1-cpab0580__11661__35212.1706535222.jpg?c=1 "ESR1 Monoclonal Antibody [LSERASC1] (CPAB0580)")
- SKU:
- CPAB0580
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG
- Clone:
- LSERASC1
- Applications:
- WB
- Applications:
- IHC
- Applications:
- FC
![ESR1 Monoclonal Antibody [LSERASC1] (CPAB0580)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58801/63983/esr1-monoclonal-antibody-lserasc1-cpab0580__11661__35212.1706535222.jpg?c=1&imbypass=on "ESR1 Monoclonal Antibody [LSERASC1] (CPAB0580)")
Description
system_update_alt Datasheet
| Product Name: | ESR1 Antibody |
| Product Sku: | CPAB0580 |
| Size: | 500μg |
| Host Species: | Mouse |
| Immunogen: | Recombinant human ER-alpha. |
| Clone: | LSERASC1. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, Immunohistochemistry, Flow Cytometry |
| Purification Method: | Protein A |
| Isotype: | IgG |
| Background: | Estrogen receptors ? (ER?, ER; NR3A1) is a member of the steroid hormone receptor family. ER? is a ligand-activated transcription factor. ER? contain DNA binding and ligand binding domains. ER? is expressed in a wide variety of tissues, including ovary, uterus, breast, prostate, testis, epididymis, bones, bladder, kidney, heart, vessel wall, pituitary gland and hypothalamus. ER plays a variety of important roles in the maintenance of the reproductive, cardiovascular, musculoskeletal and central nervous systems. The natural ligand for ER is 17?-estradiol, the classical estrogenic compound. The binding of estrogen to ER induces a conformational change and triggers a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. |
| Synonyms: | ER-alpha |
| Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
Related Products
IκBα Monoclonal Antibody
OverviewProduct Name:IκBα Monoclonal AntibodyProduct Code:CAB24909Reactivity:Human, Mouse, RatApplications:Western blotting, Immu
Chk1 Monoclonal Antibody
OverviewProduct Name:Chk1 Monoclonal AntibodyProduct Code:CAB22055Reactivity:HumanApplications:Western blotting
HN1 Monoclonal Antibody
OverviewProduct Name:HN1 Monoclonal AntibodyProduct Code:CAB23553Reactivity:Human, MouseApplications:Western blotting
RAB5A Monoclonal Antibody
OverviewProduct Name:RAB5A Monoclonal AntibodyProduct Code:CAB23955Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
Palladin Monoclonal Antibody
OverviewProduct Name:Palladin Monoclonal AntibodyProduct Code:CAB23566Reactivity:HumanApplications:Western blotting