ERK1 Monoclonal Antibody (CAB21975)
- SKU:
- CAB21975
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | ERK1 Monoclonal Antibody |
| Product Code: | CAB21975 |
| Reactivity: | Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51164 |
| Reactivity: | Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:10000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Rat brain |
| Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK1ERK1/2 (P27361/P28482). |
| Sequence: | FLTEY VATRW YRAPE IMLNS KGYTK SIDIW SVGCI LAEML SNRPI FPGKH YLDQL NHILG ILGSP SQEDL NCIIN MKARN YLQSL PSKTK VAWAK LFPKS D/LNS KGYTK SIDIW SVGCI LAEML SNRPI FPGKH YLDQL NHILG ILGSP SQEDL NCIIN LKARN YLLSL PHKNK VPWNR LFPNA DSKAL DLLDK MLTFN PHK |
| Synonyms: | ERK1, ERT2, ERK-1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, p44-ERK1, p44-MAPK |
| Calculated MW: | 43kDa |
| Observed MW: | 44kDa |
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