ERF Transcription Factor Activity Assay
- SKU:
- TFAB00097
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- ERF
- Reactivity:
- Human
- Reactivity:
- Mouse
Description
| Product Name: | ERF Transcription Factor Activity Assay |
| Product Code: | TFAB00097 |
| Target: | ERF |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie ERF transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | ERF: potent transcriptional repressor that binds to the H1 element of the ETS2 promoter. Belongs to the ETS family of transcription factors. Its function is regulated by phosphorylation. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 19q13 Cellular Component: cytosol; Golgi apparatus; nucleoplasm; nucleus Molecular Function:sequence-specific DNA binding; transcription corepressor activity Biological Process: cell cycle; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent Disease: Craniosynostosis 4 |
| NCBI Summary: | ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P50548 |
| NCBI GenInfo Identifier: | 50403684 |
| NCBI Gene ID: | 2077 |
| NCBI Accession: | P50548.2 |
| UniProt Secondary Accession: | P50548,Q59G38, Q9UPI7, B2RAP1, B7Z4R0, |
| UniProt Related Accession: | P50548 |
| Molecular Weight: | 49,965 Da |
| NCBI Full Name: | ETS domain-containing transcription factor ERF |
| NCBI Synonym Full Names: | ETS2 repressor factor |
| NCBI Official Symbol: | ERF |
| NCBI Official Synonym Symbols: | PE2; CRS4; PE-2 |
| NCBI Protein Information: | ETS domain-containing transcription factor ERF |
| UniProt Protein Name: | ETS domain-containing transcription factor ERF |
| UniProt Synonym Protein Names: | Ets2 repressor factor; PE-2 |
| Protein Family: | Essential recombination function protein |
| UniProt Gene Name: | ERF |
| UniProt Entry Name: | ERF_HUMAN |
